Effect and mechanism of acupuncture on Alzheimer’s disease: A review

Published on March 3, 2023

Just like the world is facing an aging population, the field of medicine is faced with the urgent challenge of Alzheimer’s disease (AD). AD brings about cognitive impairment, affecting daily life and causing abnormal psychiatric symptoms. While drug therapy has been the go-to treatment for AD patients, it doesn’t always work for everyone and can even lead to severe sleep disorders. That’s where acupuncture comes in, with its unique approach and proven reliability in treating AD. Research has uncovered the neurobiological mechanisms behind acupuncture’s effectiveness in AD treatment, solidifying its positive impact. By examining biochemical changes and specific actions within the body, acupuncture has showcased its therapeutic benefits for AD. As studies continue to intensify, it’s clear that acupuncture will play a significant role in the future of AD treatment.

With the development trend of an aging society, Alzheimer’s disease (AD) has become an urgent problem in the field of medicine worldwide. Cognitive impairment in AD patients leads to a decline in the ability to perform daily living and abnormalities in behavior and personality, causing abnormal psychiatric symptoms, which seriously affect the daily life of patients. Currently, mainly drug therapy is used for AD patients in the clinic, but a large proportion of patients will experience drug efficacy not working, and even some drugs bring severe sleep disorders. Acupuncture, with its unique concept and treatment method, has been validated through a large number of experiments and proved its reliability of acupuncture in the treatment of AD. Many advances have been made in the study of the neurobiological mechanisms of acupuncture in the treatment of AD, further demonstrating the good efficacy and unique advantages of acupuncture in the treatment of AD. This review first summarizes the pathogenesis of AD and then illustrates the research progress of acupuncture in the treatment of AD, which includes the effect of acupuncture on the changes of biochemical indicators in AD in vivo and the specific mechanism of action to exert the therapeutic effect. Changes in relevant indicators of AD similarly further validate the effectiveness of acupuncture treatment. The clinical and mechanistic studies of acupuncture in the treatment of AD are intensified to fit the need for social development. It is believed that acupuncture will achieve new achievements in the treatment of AD as research progresses.

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