Classic serotonergic psychedelics, such as lysergic acid diethylamide (LSD), psilocybin, and dimethyltryptamine (DMT), are potent psychoactive drugs capable of inducing marked changes in subjective experience [1]. All of these compounds share serotonin 2A agonist properties, which account for most of their characteristic psychological effects [2,3]. Preliminary clinical trials suggest that psychedelic drug administration coupled with supportive psychotherapy has transdiagnostic efficacy in the treatment of mental health conditions, including depression, end-of-life distress, tobacco addiction, and alcoholism [4].