The Inflammatory Diet: A Risk for Cognitive Impairment

Published on January 4, 2023

Imagine your brain is a delicate instrument, like a finely tuned piano. Now imagine that the food you eat has the power to either harmonize or disrupt the beautiful melody of your brain. That’s exactly what researchers explored in a recent meta-analysis. They investigated the connection between the Dietary Inflammatory Index (DII) and cognitive impairment, a pressing global health concern. The DII is a score that measures how pro-inflammatory or anti-inflammatory a person’s diet is. After analyzing nine observational studies with over 19,000 subjects, they discovered that a higher DII was associated with an increased risk of cognitive impairment. This means that a pro-inflammatory diet could potentially harm your brain’s performance and health. The findings were consistent whether the studies were cross-sectional or cohort-based. These results suggest that maintaining a healthy, anti-inflammatory diet could be an essential factor in preserving cognitive function and reducing the risk of cognitive decline as we age. Intrigued? Delve deeper into the research to discover more about the impact of diet on brain health.

AimsCognitive impairment is an increasingly urgent global public health challenge. Dietary Inflammatory Index (DII) is a literature-derived score that links diet to inflammation. The relationship between DII and cognitive impairment remains controversial. Therefore, our study aimed to analysis the role of DII on the risk of cognitive impairment by meta-analysis.MethodsPubMed, Cochrane Library, MEDLINE, Web of Science and EMBASE databases were searched up to July 2022. Newcastle–Ottawa scale (NOS) and Joanna Briggs Institute (JBI) Checklist were performed to estimate the quality of studies.ResultsNine observational studies with 19,379 subjects were included. Our study found that higher DII could elevate the risk of cognitive impairment (OR = 1.46, 95%CI = 1.26, 1.69). Meanwhile, the OR of cognitive impairment was 1.49 (95%CI = 1.21, 1.83) for cross-sectional studies and 1.42 (95%CI = 1.12, 1.79) for cohort studies, respectively.ConclusionOur meta-analysis indicated that higher DII (indicating a more pro-inflammatory diet) is related to increased risk of cognitive impairment.

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