We thank Dunsmoor et al. [1] for their timely and comprehensive examination of how salient events, including novelty and emotion, can save mundane memories from oblivion when encountered in close temporal proximity – an effect sometimes referred to as ‘memory’s penumbra’. We specifically applaud their efforts in linking neurobiological mechanisms as identified in rodents to emerging behavioral findings in humans, while explaining these in light of existing memory models. They address the synaptic-tagging-and-capture hypothesis – for which two conditions are indispensable: (i) local setting of synaptic tags generated by appropriate synaptic activity; and (ii) availability of plasticity-related proteins (PRPs) that are synthesized as a result of the activation of neuromodulatory systems in a time-dependent manner [2] – to explain how on a neuronal level an initially weak memory trace becomes stable when a salient event is experienced during a critical time window around it.
Read Full Article (External Site)
Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
Armed with a Master of Science degree and a Ph.D. in his field, Dr. Lowemann has consistently been at the forefront of research and innovation, delving into ways to optimize human performance, cognition, and overall well-being. His work at the Institute revolves around a profound commitment to harnessing cutting-edge science and technology to help individuals lead more fulfilling and intelligent lives.
Dr. Lowemann’s influence extends to the educational platform BetterSmarter.me, where he shares his insights, findings, and personal development strategies with a broader audience. His ongoing mission is shaping the way we perceive and leverage the vast capacities of the human mind, offering invaluable contributions to society’s overall success and collective well-being.