Exercise Shapes Our Genes! Study Finds Twin Connection

Published on December 8, 2022

Move those muscles and change your genes! A fascinating study on twins reveals that regular exercise can lead to beneficial changes in our epigenomes, the molecular processes surrounding our DNA. By comparing identical twins, scientists discovered that the more physically active sibling in each pair had a lower risk of metabolic disease, as indicated by their waist size and body mass index. These differences were mirrored in their epigenetic marks, which play a vital role in gene expression. The active twins showcased marks linked to reduced risk of metabolic syndrome, a condition associated with heart disease, stroke, and type 2 diabetes. This exciting research suggests that our lifestyle choices, such as exercise, play a significant role in modifying the markers of genetic disease, rather than just our inherited genetics. So let’s lace up our sneakers and hit the gym to shape our destiny!

Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates. The study found that the more physically active siblings in identical twin pairs had lower signs of metabolic disease, measured by waist size and body mass index. This also correlated with differences in their epigenomes, the molecular processes that are around DNA and independent of DNA sequence, but influence gene expression. The more active twins had epigenetic marks linked to lowered metabolic syndrome, a condition that can lead to heart disease, stroke and type 2 diabetes. Since the identical twins have the same genetics, the study suggests that markers of metabolic disease are strongly influenced by how a person interacts with their environment as opposed to just their inherited genetics.

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