Revolutionary AI Approach to Leukemia Prediction!

Published on November 24, 2022

Imagine your immune system as a bustling city, with different types of white blood cells (WBCs) playing different roles. But sometimes, chaos strikes in the form of acute lymphoblastic leukemia (ALL), when immature WBCs run amok, attacking healthy cells. Detecting ALL early is crucial for effective treatment and survival. Manual prediction is slow and expensive, so researchers have developed an ingenious computer vision-based approach using artificial intelligence (AI) algorithms: K-Nearest Neighbor (KNN), Support Vector Machine (SVM), Random Forest (RF), and Naive Bayes (NB). By analyzing a dataset of cancer and healthy cells, this AI ensemble model accurately predicts ALL with an impressive 90.0% accuracy. It starts by cropping imperfect images to focus on essential details, then extracts features using deep neural networks like VGG19, ResNet50, or ResNet101. To fine-tune the predictions, the dataset undergoes data scaling using a technique called MinMaxScaler normalization. Additionally, ASOVA, RFE, and RF algorithms are employed for feature selection. The results show SVM triumphs as the top performer among all algorithms. This groundbreaking AI approach could revolutionize leukemia prediction and save countless lives!

Leukemia (blood cancer) diseases arise when the number of White blood cells (WBCs) is imbalanced in the human body. When the bone marrow produces many immature WBCs that kill healthy cells, acute lymphocytic leukemia (ALL) impacts people of all ages. Thus, timely predicting this disease can increase the chance of survival, and the patient can get his therapy early. Manual prediction is very expensive and time-consuming. Therefore, automated prediction techniques are essential. In this research, we propose an ensemble automated prediction approach that uses four machine learning algorithms K-Nearest Neighbor (KNN), Support Vector Machine (SVM), Random Forest (RF), and Naive Bayes (NB). The C-NMC leukemia dataset is used from the Kaggle repository to predict leukemia. Dataset is divided into two classes cancer and healthy cells. We perform data preprocessing steps, such as the first images being cropped using minimum and maximum points. Feature extraction is performed to extract the feature using pre-trained Convolutional Neural Network-based Deep Neural Network (DNN) architectures (VGG19, ResNet50, or ResNet101). Data scaling is performed by using the MinMaxScaler normalization technique. Analysis of Variance (ANOVA), Recursive Feature Elimination (RFE), and Random Forest (RF) as feature Selection techniques. Classification machine learning algorithms and ensemble voting are applied to selected features. Results reveal that SVM with 90.0% accuracy outperforms compared to other algorithms.

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