Exploring the Landscape of Alzheimer’s Research: A Bibliometric Analysis

Published on October 18, 2022

Imagine you’re a detective, searching through a vast library for clues to solve a mysterious case. Well, scientists are detectives too, and their library consists of research articles! In this study, researchers conducted a bibliometric analysis to explore the landscape of Alzheimer’s disease (AD) research related to non-coding RNAs (ncRNAs). They searched through thousands of articles published in the past decade to collect valuable information. Using powerful visualization tools, they uncovered fascinating insights: the most popular journal for AD research, the top countries, institutions, and authors contributing to the field, and the exciting research hotspots. They discovered that ncRNAs, particularly microRNAs, were central to understanding AD and its mechanism. Furthermore, they found that the majority of research focused on animal and cellular levels, shedding light on new directions for future studies. But why stop here? If you want to dive deeper into this captivating field, grab your magnifying glass and explore the underlying research yourself!

BackgroundNon-coding RNAs (ncRNA) are a kind of RNA that does not encode protein, which play an important role in Alzheimer’s disease (AD). However, there is a lack of bibliometric analysis and visualization analysis of the research related to AD and ncRNAs.Materials and methodsLiterature related to AD and ncRNAs in the last decade were searched through the Web of Science Core Collection (WOSCC). The relevant information from all the searched articles was collected. The bibliometric visualization website, CiteSpace, and VOSviewer were used for visualization analysis of countries/regions, institutions, authors, and keywords.ResultsIn total, 1,613 kinds of literature were published in the field. Literature in this field were published in 494 journals. The Journal of Alzheimer’s Disease was the most popular journal. China, Louisiana State University System, and Lukiw WJ were the countries/regions, institutions, and authors with the highest scientific productivity, respectively. The research hotspots in this field focused on the role and mechanism of ncRNAs, especially microRNAs, in AD. The level of research was mainly based on basic research, focusing on animal and cellular levels, and related to proteomics. “Circular RNAs,” “regulation of neuroinflammation,” and “tau protein” were the future research directions.ConclusionTaken together, the field of AD and ncRNAs is developing well. The research hotspots and frontiers in this field can provide a reference for researchers to choose their research direction.

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