Unlocking the Potential of TMS for Stroke Survivors

Published on September 26, 2022

Imagine your brain is a city, and after a stroke, some buildings in the city are damaged. Restoring blood circulation is like repairing the roads to prevent further damage. But what about rebuilding the buildings? That’s where transcranial magnetic stimulation (TMS) comes in! TMS is like having skilled architects and construction workers who can assess the damage and modulate activity in specific areas of the brain. In this case, TMS targets the primary motor cortex (M1) to help stroke survivors regain their motor functions. But here’s the exciting part: TMS may also be able to help with other issues beyond movement, such as difficulties with swallowing, speech, pain, mood, and thinking abilities. Although there’s still a lot to learn about how it all works, researchers are seeing promising results. So if you’re someone interested in the fascinating world of neurorehabilitation, check out the full article to dive deeper into the potential of TMS for stroke survivors!

Stroke is a leading cause of morbidity and mortality among elderly populations worldwide. During the early phase of stroke, restoring blood circulation is of utmost importance to protect neurons from further injury. Once the initial condition is stabilized, various rehabilitation techniques can be applied to help stroke survivors gradually regain their affected functions. Among these techniques, transcranial magnetic stimulation (TMS) has emerged as a novel method to assess and modulate cortical excitability non-invasively and aid stroke survivors in the rehabilitation process. Different cortical regions have been targeted using TMS based on the underlying pathology and distorted function. Despite the lack of a standard operational procedure, repetitive TMS (rTMS) of the primary motor cortex (M1) is considered a promising intervention for post-stroke motor rehabilitation. However, apart from the motor response, mounting evidence suggests that M1 stimulation can be employed to treat other symptoms such as dysphagia, speech impairments, central post-stroke pain, depression, and cognitive dysfunction. In this mini-review, we summarize the therapeutic uses of rTMS stimulation over M1 in stroke survivors and discuss the potential mechanistic rationale behind it.

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