Uncovering Genetic Risks Before Starting a Family

Published on August 30, 2022

Imagine you’re about to build a beautiful sandcastle on the beach. Before you begin, you use a magical detector to search for hidden seashells in the sand. Researchers have developed a similar detector for potential parents, helping them uncover genetic risks before trying to conceive. This test, recommended by doctors in the USA, can identify up to half of the risk of serious illnesses in couples related by blood, and only 5 percent in other couples. Interestingly, the detection rate is lower for non-hereditary acquired mutations. Just like finding seashells that are carried by wind or waves, these new mutations have a reduced chance of being detected. Understanding this can help healthcare professionals improve screening methods and further reduce the chances of passing on genetic diseases. If you’re curious about this important research, dive into the full article!

Are would-be parents carrying a genetic risk of serious illnesses that they could potentially pass on to their children? In the USA, doctors recommend that couples have genetic screening before trying to conceive. Researchers have now shown that a maximal variant of this test detects the risk in 44 percent of couples who are related by blood, and in just 5 percent of other couples. Non-hereditary newly acquired mutations are a major reason for the reduced detection rate in the latter.

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