The Brain’s Workout: How Exercise Boosts Brain Function in Older Adults

Published on May 18, 2022

Just like how lifting weights strengthens your muscles, aerobic exercise training (AT) can do wonders for your brain! As we get older and lead sedentary lifestyles, our cerebrovascular function and cognitive abilities decline. But fear not, because AT is here to save the day! In a study with sedentary, obese, older adults, researchers investigated the effects of 16 weeks of AT on cerebrovascular and cognitive function. The results were astonishing! Participants who engaged in AT saw improvements in their cerebrovascular responsiveness to both physiological and cognitive stimuli. Not only that, but their composite cognitive score also went up! The more exercise sessions they completed, the better their cognitive response became. It’s like flexing your brain muscles with each workout session! This study sheds light on the importance of regular exercise for maintaining a healthy brain as we age. So, why not lace up your sneakers and embark on an exercise adventure? Your brain will thank you!

Cerebrovascular function and cognition decline with age and are further exacerbated by obesity and physical inactivity. This decline may be offset by aerobic exercise training (AT). We investigated the effects of 16 weeks AT on cerebrovascular and cognitive function in sedentary, obese, older adults. Twenty-eight participants were randomly allocated to AT or a control group. Before and after the intervention, transcranial Doppler ultrasonography was used to measure the cerebrovascular responsiveness (CVR) to physiological (hypercapnia, 5% carbon dioxide) and cognitive stimuli. AT increased the CVR to hypercapnia (98.5 ± 38.4% vs. 58.0 ± 42.0%, P = 0.021), CVR to cognitive stimuli (25.9 ± 6.1% vs. 16.4 ± 5.4%, P < 0.001) and total composite cognitive score (111 ± 14 vs. 104 ± 14, P = 0.004) compared with the control group. A very strong relationship was observed between the number of exercise sessions completed and CVR to cognitive stimuli (r = 0.878, P < 0.001), but not for CVR to hypercapnia (r = 0.246, P = 0.397) or total composite cognitive score (r = 0.213, P = 0.465). Cerebrovascular function and cognition improved following 16 weeks of AT and a dose-response relationship exists between the amount of exercise sessions performed and CVR to cognitive stimuli.

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