Running boosts brain health via nerve-growth protein

Published on May 18, 2022

Scientists have discovered that running increases the levels of a protein involved in the growth of brain cells, resulting in higher levels of dopamine, a hormone associated with feelings of happiness and motivation. This finding helps to explain why regular running has been linked to improved brain health and protection against nerve cell damage. Previous studies have already established the connection between exercise-induced elevation of dopamine levels and enhancements in learning and memory. However, the exact mechanism by which these factors interact was previously unknown. With this new discovery, we can visualise the relationship between running, the release of dopamine, and the presence of brain-derived neurotrophic factor (BDNF), a chemical that triggers the production of dopamine. By exploring the underlying research further, we can uncover the full extent of running’s impact on brain health and potential therapeutic applications for conditions related to dopamine dysfunction.

Exercise increases levels of a chemical involved in brain cell growth, which bolsters the release of the ‘feel good’ hormone dopamine, a new study shows. Dopamine is known to play a key role in movement, motivation, and learning. Experts have long understood that regular running raises dopamine activity in the brain and may protect nerve cells from damage. In addition, past research has tied exercise-driven boosts in the dopamine-triggering chemical called brain-derived neurotrophic factor (BDNF) and in dopamine levels to improvements in learning and memory. However, the precise way these three factors interact has until now remained unclear.

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