Imagine the gastrointestinal tract as a bustling city, filled with millions of neurons that make up the enteric nervous system (ENS). This system acts as the bridge between the gut microbiota and our neurological well-being. Just like how a well-functioning transportation network keeps a city running smoothly, the ENS works with intestinal microbes, the immune system, and hormones to maintain a stable gut environment. Scientists have been studying how changes in gut microbes can affect both the ENS and the central nervous system (CNS), which includes our brain. The research so far suggests that gut microbes have a vital role to play in various neurological disorders. However, it’s important to note that the direct cause-and-effect relationship between microbial changes and these disorders is still being investigated. This review article summarizes the potential impact of GI microbiota on the ENS and CNS, shedding new light on our understanding of neurological conditions. Curious to learn more? Dive into the fascinating research behind this emerging field!
The gastrointestinal (GI) tract plays an essential role in food digestion, absorption, and the mucosal immune system; it is also inhabited by a huge range of microbes. The GI tract is densely innervated by a network of 200–600 million neurons that comprise the enteric nervous system (ENS). This system cooperates with intestinal microbes, the intestinal immune system, and endocrine systems; it forms a complex network that is required to maintain a stable intestinal microenvironment. Understanding how gut microbes influence the ENS and central nervous system (CNS) has been a significant research subject over the past decade. Moreover, accumulating evidence from animal and clinical studies has revealed that gut microbiota play important roles in various neurological diseases. However, the causal relationship between microbial changes and neurological disorders currently remains unproven. This review aims to summarize the possible contributions of GI microbiota to the ENS and CNS. It also provides new insights into furthering our current understanding of neurological disorders.
Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
Armed with a Master of Science degree and a Ph.D. in his field, Dr. Lowemann has consistently been at the forefront of research and innovation, delving into ways to optimize human performance, cognition, and overall well-being. His work at the Institute revolves around a profound commitment to harnessing cutting-edge science and technology to help individuals lead more fulfilling and intelligent lives.
Dr. Lowemann’s influence extends to the educational platform BetterSmarter.me, where he shares his insights, findings, and personal development strategies with a broader audience. His ongoing mission is shaping the way we perceive and leverage the vast capacities of the human mind, offering invaluable contributions to society’s overall success and collective well-being.