Month: April 2022

Cracking the Code of UPS in Stroke

In the puzzling world of stroke research, secondary damage factors like inflammation, oxidative stress, and mitochondrial dysfunction play a significant role. Current treatments for these damages prove to be disheartening, leaving scientists hungry for innovative strategies. Enter the ubiquitin proteasome system (UPS), the mastermind behind processing key proteins in our cells. This system is vital […]

Published on April 7, 2022

The Impact of Treatment on Thrombolysis Related Hemorrhagic Transformation

Like chefs experimenting with different ingredients in a recipe, doctors in China conducted a multi-center study to investigate the best way to manage thrombolysis related hemorrhagic transformation (HT) and reduce the risk of death and hematoma expansion. They reviewed the medical records of 538 patients who had received thrombolytics for ischemic stroke and found that […]

Published on April 7, 2022

A Potential Mechanism for Targeting Aggregates With Proteasomes and Disaggregases in Liquid Droplets

Imagine your room is filled with clutter, making it difficult to find what you need and hindering your daily activities. Similarly, neurodegenerative disorders like dementia are marked by the accumulation of protein aggregates, which create a messy environment in brain cells. Scientists have discovered a potential mechanism for targeting these aggregates with proteasomes and disaggregases: […]

Published on April 7, 2022