Month: March 2022

Glucocerebrosidase Mutations: Links to Dysfunctional Mitochondria and Lysosomes in Parkinson’s Disease

Imagine a bustling city with an intricate transportation system, keeping everything running smoothly. Now, picture this system starting to break down, causing traffic jams and delays throughout the city. In a similar way, mutations in the glucocerebrosidase (GBA) gene can disrupt the delicate balance of mitochondria and lysosomes in Parkinson’s disease (PD). GBA mutations, the […]

Published on March 23, 2022

GBA Mutations in Parkinson’s: Mitochondrial & Lysosomal Dysfunction

Imagine your body is a city, with different systems and structures working together to keep everything running smoothly. In Parkinson’s disease (PD), it’s like there’s a traffic jam causing havoc in two key areas: the mitochondria and the lysosomes. Scientists have discovered that mutations in the glucocerebrosidase (GBA) gene, which produces an enzyme called glucocerebrosidase […]

Published on March 23, 2022

Unlocking the Mystery of Depression in Parkinson’s Disease

Imagine your brain is a complex network of roads, each region responsible for different functions. In people with Parkinson’s disease (PD), depression can be an unwelcome passenger on this journey. Scientists wanted to understand how depression affects the brain in PD, so they embarked on a meta-analysis adventure! They collected data from previous studies and […]

Published on March 23, 2022