Month: January 2022

Gut Microbiota Alteration Is Associated With Cognitive Deficits in Genetically Diabetic (Db/db) Mice During Aging

Recent studies have revealed that the microbiota may be implicated in diabetes-related cognitive dysfunction. However, the relationship between gut microbiota and cognitive dysfunction during the progression of type 2 diabetes remains elusive. We used 16S rRNA sequencing combined with conventional behavioral tests to explore the longitudinal changes of gut microbiota and cognition in diabetic db/db […]

Published on January 26, 2022

Radiomic Features of the Hippocampus for Diagnosing Early-Onset and Late-Onset Alzheimer’s Disease

Background: Late-onset Alzheimer’s disease (LOAD) and early-onset Alzheimer’s disease (EOAD) are different subtypes of AD. This study aimed to build and validate radiomics models of the hippocampus for EOAD and young controls (YCs), LOAD and old controls (OCs), as well as EOAD and LOAD.Methods: Thirty-six EOAD patients, 36 LOAD patients, 36 YCs, and 36 OCs […]

Published on January 26, 2022

Semantic tiles or hub-and-spokes?

New results from Popham et al. generate ‘semantic maps’ from spoken narratives and movies that appear remarkably aligned near visual cortex. We consider whether such findings are consistent with the hub-and-spokes view of semantic representation or whether they require a rethinking of the cortical knowledge system. Read Full Article (External Site) Dr. David LowemannDr. David […]

Published on January 26, 2022