Month: December 2021

Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons

The decline in brain function during aging is one of the most critical health problems nowadays. Although senescent astrocytes have been found in old-age brains and neurodegenerative diseases, their impact on the function of other cerebral cell types is unknown. The aim of this study was to evaluate the effect of senescent astrocytes on the […]

Published on December 1, 2021

Transitions in the Cognitive Frailty States in Community-Living Older Adults: A 6-Year Prospective Cohort Study

Background: Frailty is a multidimensional concept, including physical, cognitive, social, sensorial, psychological, and nutritional phenotypes. Among these phenotypes, cognitive frailty is the most widely investigated, which is related to many adverse health outcomes in older individuals. Whether cognitive frailty is dynamic or how these frail phenotypes interact remains an open issue. We studied the rate […]

Published on December 1, 2021

Pacemaker, Defibrillator Surgery Can Increase Risk for Opioid Abuse

People who are prescribed opioid painkillers after receiving a heart pacemaker or defibrillator may be at risk for opioid abuse – and the higher the initial dose, the greater the risk, according to a new study. “The significance of this study is to make other… Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, […]

Published on December 1, 2021