Assessing the progression of movement disorders such as Parkinson’s Disease (PD) is key in adjusting therapeutic interventions. However, current methods are still based on subjective factors such as visual observation, resulting in significant inter-rater variability on clinical scales such as UPDRS. Recent studies show the potential of sensor-based methods to address this limitation. The goal of this systematic review is to provide an up-to-date analysis of contactless sensor-based methods to estimate hand dexterity UPDRS scores in PD patients. Two hundred and twenty-four abstracts were screened and nine articles selected for analysis. Evidence obtained in a cumulative cohort of n = 187 patients and 1, 385 samples indicates that contactless sensors, particularly the Leap Motion Controller (LMC), can be used to assess UPDRS hand motor tasks 3.4, 3.5, 3.6, 3.15, and 3.17, although accuracy varies. Early evidence shows that sensor-based methods have clinical potential and might, after refinement, complement, or serve as a support to subjective assessment procedures. Given the nature of UPDRS assessment, future studies should observe whether LMC classification error falls within inter-rater variability for clinician-measured UPDRS scores to validate its clinical utility. Conversely, variables relevant to LMC classification such as power spectral densities or movement opening and closing speeds could set the basis for the design of more objective expert systems to assess hand dexterity in PD.
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Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
Armed with a Master of Science degree and a Ph.D. in his field, Dr. Lowemann has consistently been at the forefront of research and innovation, delving into ways to optimize human performance, cognition, and overall well-being. His work at the Institute revolves around a profound commitment to harnessing cutting-edge science and technology to help individuals lead more fulfilling and intelligent lives.
Dr. Lowemann’s influence extends to the educational platform BetterSmarter.me, where he shares his insights, findings, and personal development strategies with a broader audience. His ongoing mission is shaping the way we perceive and leverage the vast capacities of the human mind, offering invaluable contributions to society’s overall success and collective well-being.