Background: Neurofilament light chain (NfL) is a validated biofluid marker of neuroaxonal damage with great potential for monitoring patients with neurodegenerative diseases. We aimed to further validate the clinical utility of plasma (p) vs. CSF (c) NfL for distinguishing patients with Amyotrophic Lateral Sclerosis (ALS) from ALS mimics. We also assessed the association of biomarker […]
Published on October 22, 2021
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. However, its cellular and molecular mechanisms still wrap in the mist. This is partially caused by the absence of appropriate animal models mimicking sporadic PD that constitutes the majority of cases. Previously, we reported that a cysteine protease, asparagine endopeptidase (AEP), is activated in […]
Published on October 22, 2021
Getting the right amount of sleep – not too much and not too little – could reduce your risk of mental decline as you age, even if you have early Alzheimer’s disease, a new study claims. Poor sleep and Alzheimer’s disease are both associated with thinking (“cognitive”)… Read Full Article (External Site) Dr. David LowemannDr. […]
Published on October 22, 2021
