Month: October 2021

Stability Evaluation of Brain Changes in Parkinson’s Disease Based on Machine Learning

Structural MRI (sMRI) has been widely used to examine the cerebral changes that occur in Parkinson’s disease (PD). However, previous studies have aimed for brain changes at the group level rather than at the individual level. Additionally, previous studies have been inconsistent regarding the changes they identified. It is difficult to identify which brain regions […]

Published on October 26, 2021

Deep-Learning Radiomics for Discrimination Conversion of Alzheimer’s Disease in Patients With Mild Cognitive Impairment: A Study Based on 18F-FDG PET Imaging

Objectives: Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder and the most common form of dementia in the older people. Some types of mild cognitive impairment (MCI) are the clinical precursors of AD, while other MCI forms tend to remain stable over time and do not progress to AD. To discriminate MCI patients at […]

Published on October 26, 2021

Arterial Stiffening Moderates the Relationship Between Type-2 Diabetes Mellitus and White Matter Hyperintensity Burden in Older Adults With Mild Cognitive Impairment

Background: Cerebrovascular dysfunction has been proposed as a possible mechanism underlying cognitive impairment in the context of type 2 diabetes mellitus (DM). Although magnetic resonance imaging (MRI) evidence of cerebrovascular disease, such as white matter hyperintensities (WMH), is often observed in DM, the vascular dynamics underlying this pathology remain unclear. Thus, we assessed the independent […]

Published on October 26, 2021