IntroductionDysregulation of the RING finger protein 213 (RNF213) gene impairs vascular formation in experimental animal models. In addition, vascular abnormalities in the circle of Willis are associated with cerebrovascular disease. Here, we evaluated the relationship between the East Asian founder variant RNF213 p.R4810K and consequent anatomical variations in the circle of Willis in cerebrovascular disease.Patients […]
Published on July 15, 2021
Background: Estrogen deficiency contributes to the development of Alzheimer’s disease (AD) in menopausal women. In the current study, we examined the impact of estrogen deficiency on mitochondrial function and cognition using a postmenopausal mouse model.Methods: Bilateral ovariectomy was conducted in adult females C57BL/6J. Cognitive function was examined using the Morris water maze (MWM) test at […]
Published on July 15, 2021
Combined perceptions of the risk and availability of cannabis influence the risk of cannabis use more than perceived risk and perceived availability alone, according to a new study. Researchers observed that those who perceived cannabis as low-risk and available were more likely to report using the drug in the past year and almost daily compared […]
Published on July 15, 2021
