Month: July 2021

Insights Into Parkin-Mediated Mitophagy in Alzheimer’s Disease: A Systematic Review

Background: Parkin-mediated mitophagy is the dominant mitophagy pathway of neural cells. Its restoration will result in prevention of cognitive decline, including Alzheimer’s disease (AD). The role of this mitophagy pathway in neurodegenerative diseases has drawn attention in recent years. The two main pathological proteins in AD, amyloid β (Aβ) and human Tau (hTau), interfere with […]

Published on July 29, 2021

Exploring the Interactions Between Neurophysiology and Cognitive and Behavioral Changes Induced by a Non-pharmacological Treatment: A Network Approach

Dementia due to Alzheimer’s disease (AD) is a neurological syndrome which has an increasing impact on society, provoking behavioral, cognitive, and functional impairments. AD lacks an effective pharmacological intervention; thereby, non-pharmacological treatments (NPTs) play an important role, as they have been proven to ameliorate AD symptoms. Nevertheless, results associated with NPTs are patient-dependent, and new […]

Published on July 29, 2021

Rationalizing constraints on the capacity for cognitive control

Humans are remarkably limited in: (i) how many control-dependent tasks they can execute simultaneously, and (ii) how intensely they can focus on a single task. These limitations are universal assumptions of most theories of cognition. Yet, a rationale for why humans are subject to these constraints remains elusive. This feature review draws on recent insights […]

Published on July 29, 2021