Rare mutations in the mitochondrial protein coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) are associated with Parkinson’s disease (PD) and other Lewy body disorders. CHCHD2 is a bi-organellar mediator of oxidative phosphorylation, playing crucial roles in regulating electron flow in the mitochondrial electron transport chain and acting as a nuclear transcription factor for a cytochrome c oxidase […]
Published on April 22, 2021
Cognitive control relies on distributed and potentially high-dimensional frontoparietal task representations. Yet, the classical cognitive neuroscience approach in this domain has focused on aggregating and contrasting neural measures – either via univariate or multivariate methods – along highly abstracted, 1D factors (e.g., Stroop congruency). Here, we present representational similarity analysis (RSA) as a complementary approach […]
Published on April 22, 2021
Research on how obesity impacts the diagnosis, management and outcomes of heart and blood vessel disease, heart failure and arrhythmias is summarized in a new statement. Waist circumference, an indicator of abdominal obesity, should be regularly measured as it is a potential warning sign of increased cardiovascular disease risk. Interventions that lead to weight loss […]
Published on April 22, 2021
