Month: February 2021

The Connectivity Fingerprints of Highly-Skilled and Disordered Reading Persist Across Cognitive Domains

The capacity to produce and understand written language is a uniquely human skill that exists on a continuum, and foundational to other facets of human cognition. Multivariate classifiers based on support vector machines (SVM) have provided much insight into the networks underlying reading skill beyond what traditional univariate methods can tell us. Shallow models like […]

Published on February 12, 2021

Body Temperature Is Associated With Cognitive Performance in Older Adults With and Without Mild Cognitive Impairment: A Cross-sectional Analysis

Wearable devices for remote and continuous health monitoring in older populations frequently include sensors for body temperature measurements (i.e., skin and core body temperatures). Healthy aging is associated with core body temperatures that are in the lower range of age-related normal values (36.3 ± 0.6°C, oral temperature), while patients with Alzheimer’s disease (AD) exhibit core […]

Published on February 12, 2021

The Impact of Disease Comorbidities in Alzheimer’s Disease

A wide range of comorbid diseases is associated with Alzheimer’s disease (AD), the most common neurodegenerative disease worldwide. Evidence from clinical and molecular studies suggest that chronic diseases, including diabetes, cardiovascular disease, depression, and inflammatory bowel disease, may be associated with an increased risk of AD in different populations. Disruption in several shared biological pathways […]

Published on February 12, 2021