Month: January 2021

Implementation-Independent Representation for Deep Convolutional Neural Networks and Humans in Processing Faces

Deep convolutional neural networks (DCNN) nowadays can match human performance in challenging complex tasks, but it remains unknown whether DCNNs achieve human-like performance through human-like processes. Here we applied a reverse-correlation method to make explicit representations of DCNNs and humans when performing face gender classification. We found that humans and a typical DCNN, VGG-Face, used […]

Published on January 26, 2021

Identification of Heterogeneous Subtypes of Mild Cognitive Impairment Using Cluster Analyses Based on PET Imaging of Tau and Astrogliosis

Background: Mild cognitive impairment (MCI) is a condition with diverse causes and clinical outcomes that can be categorized into subtypes. [18F]THK5351 has been known to detect reactive astrogliosis as well as tau which is accompanied by neurodegenerative changes. Here, we identified heterogeneous groups of MCI patients using THK retention patterns and a graph theory approach, […]

Published on January 26, 2021

The Involvement of Aquaporin-4 in the Interstitial Fluid Drainage Impairment Following Subarachnoid Hemorrhage

The mechanism of brain injury following subarachnoid hemorrhage (SAH) has not yet been clarified. The glymphatic system (GS), a glia-dependent waste clearance pathway, drains away soluble waste proteins and metabolic products, even some toxic factors from the brain. Aquaporin-4 (Aqp4) is highly expressed on the astrocyte foot processes and facilitates the interstitial fluid (ISF) transportation […]

Published on January 26, 2021