Month: January 2021

Improvement of Multiparametric MR Image Segmentation by Augmenting the Data With Generative Adversarial Networks for Glioma Patients

Every year thousands of patients are diagnosed with a glioma, a type of malignant brain tumor. MRI plays an essential role in the diagnosis and treatment assessment of these patients. Neural networks show great potential to aid physicians in the medical image analysis. This study investigated the creation of synthetic brain T1-weighted (T1), post-contrast T1-weighted […]

Published on January 28, 2021

Impact of Chaperone-Mediated Autophagy in Brain Aging: Neurodegenerative Diseases and Glioblastoma

Brain aging is characterized by a time-dependent decline of tissue integrity and function, and it is a major risk for neurodegenerative diseases and brain cancer. Chaperone-mediated autophagy (CMA) is a selective form of autophagy specialized in protein degradation, which is based on the individual translocation of a cargo protein through the lysosomal membrane. Regulation of […]

Published on January 28, 2021

Evolution of Apathy in Early Parkinson’s Disease: A 4-Years Prospective Cohort Study

Objective: We investigated the prevalence, evolution, associated factors, and risk factors of apathy in a cohort of patients with early-stage Parkinson’s disease (PD), who underwent a 4-years prospective follow-up.Methods: This study included 188 patients with PD (baseline disease duration Read Full Article (External Site) Dr. David LowemannDr. David Lowemann, M.Sc, Ph.D., is a co-founder of […]

Published on January 28, 2021