Prefrontal cortical and medial temporal lobe connectivity is critical for higher cognitive functions that decline in older adults. Likewise, these cortical areas are among the first to show anatomical, functional, and biochemical alterations in advanced age. The prelimbic subregion of the prefrontal cortex and the perirhinal cortex of the medial temporal lobe are densely reciprocally […]
Published on October 28, 2020
Recent studies have demonstrated that connector hubs, regions considered critical for the flow of information across neural systems, are mostly involved in neurodegenerative dementia. Considering that aging can significantly affect the brain’s intrinsic connectivity, identifying aging’s impact on these regions’ overall connection strength is important to differentiate changes associated with healthy aging from neurodegenerative disorders. […]
Published on October 28, 2020
Overgaard and Kirkeby-Hinrup conclude their comment [1] on our Opinion article [2] by asking, ‘Does SOMA entail that animals, children and many adults are not conscious?’ This question is indeed essential, and our answer is a clear: ‘We do not know, nor does anyone else.’ But we want to state right away that we believe […]
Published on October 28, 2020
