Month: March 2020

Action Potential: A Vortex Phenomena; Driving Membrane Oscillations

Hodgkin-Huxley (HH) model has been one of the most successful electrical interpretation of nerve membrane which led to revolutions in the field of computational neuroscience. On the contrary, experimental observations indicate that, an Action Potential (AP) is accompanied with certain physiological changes in the nerve membrane such as, production and absorption of heat; variation of […]

Published on March 18, 2020

Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6

Stroke remains a leading cause of death, disability, and medical care burden worldwide. However, transformation from laboratory findings toward effective pharmacological interventions for clinical stroke has been unsatisfactory. Novel evidence has been gained on the underlying mechanisms and therapeutic potential related to the transient receptor potential (TRP) channels in several disorders. The TRP superfamily consists […]

Published on March 18, 2020

Young Children Selectively Hide the Truth About Sensitive Topics

Abstract Starting in early childhood, children are socialized to be honest. However, they are also expected to avoid telling the truth in sensitive situations if doing so could be seen as inappropriate or impolite. Across two studies (total N = 358), the reasoning of 3‐ to 5‐year‐old children in such a scenario was investigated by manipulating whether […]

Published on March 18, 2020