Month: January 2020

Links Between Adiponectin and Dementia: From Risk Factors to Pathophysiology

With the aging population, dementia is becoming one of the most serious and troublesome global public health issues. Numerous studies have been seeking for effective strategies to delay or block its progression, but with little success. In recent years, adiponectin (APN) as one of the most abundant and multifunctional adipocytokines related to anti-inflammation, regulating glycogen […]

Published on January 8, 2020

Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods

Age-related brain changes likely contribute to mobility impairments, but the specific mechanisms are poorly understood. Current brain measurement approaches (e.g., functional magnetic resonance imaging (fMRI), functional near infrared spectroscopy (fNIRS), PET) are limited by inability to measure activity from the whole brain during walking. The Mind in Motion Study will use cutting edge, mobile, high-density […]

Published on January 8, 2020

Semantic Search as Pattern Completion across a Concept

What role does the hippocampus play in semantic memory? In a recent paper, Cutler et al. use a vector space model of semantics to characterize semantic search deficits in hippocampal amnesia. We relate their findings to properties of the hippocampal neural code and to controversies regarding hippocampal contributions to cognition. Read Full Article (External Site) […]

Published on January 8, 2020