Amyloid-β (Aβ) deposits and some proteins play some essential roles in AD pathogenesis. Amide proton transfer (APT) imaging as an indicator of tissue protein has shown promise for AD diseases. In this study, we chose 20 AD model rats as the experimental group and 20 sham-operated rats as the control group. They were firstly underwent Y-maze test, and then performed on a 7.0 T animal MRI scanner to acquire brain amide proton transfer image using saturation with frequency alternating RF irradiation (APTSAFARI) method. Compared with the control group, APT (3.5ppm) values of brain were significantly reduced in AD models (p
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Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
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