Understanding how neurons arrange themselves into neural networks that result in behaviors is a major goal in neuroscience. Most theoretical and experimental efforts have focused on a top-down approach which seeks to identify neuronal correlates of behaviors. This has been accomplished by effectively mapping specific behaviors to distinct neural patterns or by creating computational models […]

Although the neural mechanism supporting episodic recollection has been well characterized in younger adults, exactly how recollection is supported in older adults remains unclear. The electrophysiological correlate of recollection – the parietal retrieval success effect – for example, has been shown to be sensitive to both the amount of information recollected and the accuracy of […]

These days the important role of retinoids in adult brain functionality and homeostasis is well accepted and has been proven by genomic as well as non-genomic mechanisms. In the healthy brain, numerous biological processes e.g. cell proliferation, neurogenesis, dendritic spine formation as well as modulation of the immune system have been attributed to retinoid signaling. […]