The current ‘one size fits all’ approach to our cognitive aging population is not adequate to close the gap between cognitive health span and lifespan. In this review paper, we present a a novel model for understanding, preventing, and treating age-related cognitive impairment (ARCI) based on the concepts precision medicine. We will discuss how multiple risk factors can be classified into risk categories because of their interrelatedness in real life, the brain drivers or common mechanisms mediating brain aging, and the genetic variants that increase sensitivity to, or ameliorate, risk for ARCI. Rather than providing a definitive model of risk for ARCI and cognitive decline, the Precision Aging model is meant as a starting point to guide future research. To that end, after briefly discussing key risk categories, brain drivers, and genetic risks, we conclude with a discussion of steps that can be taken to move the field forward.
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Dr. David Lowemann, M.Sc, Ph.D., is a co-founder of the Institute for the Future of Human Potential, where he leads the charge in pioneering Self-Enhancement Science for the Success of Society. With a keen interest in exploring the untapped potential of the human mind, Dr. Lowemann has dedicated his career to pushing the boundaries of human capabilities and understanding.
Armed with a Master of Science degree and a Ph.D. in his field, Dr. Lowemann has consistently been at the forefront of research and innovation, delving into ways to optimize human performance, cognition, and overall well-being. His work at the Institute revolves around a profound commitment to harnessing cutting-edge science and technology to help individuals lead more fulfilling and intelligent lives.
Dr. Lowemann’s influence extends to the educational platform BetterSmarter.me, where he shares his insights, findings, and personal development strategies with a broader audience. His ongoing mission is shaping the way we perceive and leverage the vast capacities of the human mind, offering invaluable contributions to society’s overall success and collective well-being.