Month: May 2019

Direct Measurements of Abdominal Visceral Fat and Cognitive Impairment in Late Life: Findings From an Autopsy Study

Background: The relationship between cognitive impairment and abdominal visceral is controversial. Moreover, all studies so far used imaging studies to evaluate visceral fat and this association has not been described yet using autopsy material, which allows the direct quantification of abdominal fat. We aimed to investigate the association between direct measurements of abdominal visceral fat […]

Published on May 7, 2019

Newly Developed TV-Based Cognitive Training Games Improve Car Driving Skills, Cognitive Functions, and Mood in Healthy Older Adults: Evidence From a Randomized Controlled Trial

Background Cognitive training at a laboratory improves car driving skills of older car drivers. Nevertheless, it remains unclear whether cognitive training of other types undertaken at home has beneficial effects on driving skills. Using our developed cognitive training games that work on a TV with a set-top box in a person’s home, we investigated effects […]

Published on May 7, 2019

Transcriptional Dysregulation Study Reveals a Core Network Involving the Progression of Alzheimer’s Disease

Background: The pathogenesis of Alzheimer’s disease is associated with dysregulation at different levels from transcriptome to cellular functioning. Such complexity necessitates investigations of disease etiology to be carried out considering multiple aspects of the disease and the use of independent strategies. The established works more emphasized on the structural organization of gene regulatory network while […]

Published on May 7, 2019