Month: May 2019

A Role for Electrotonic Coupling Between Cortical Pyramidal Cells

Many brain regions communicate information through synchronized network activity. Electrical coupling among the dendrites of interneurons in the cortex has been implicated in forming and sustaining such activity in the cortex. Evidence for the existence of electrical coupling among cortical pyramidal cells, however, has been largely absent. A recent experimental study measured properties of electrical […]

Published on May 28, 2019

Involvement of Oligodendrocytes in Tau Seeding and Spreading in Tauopathies

Introduction: Human tau seeding and spreading occur following intracerebral inoculation into different grey matter regions of brain homogenates obtained from tauopathies in transgenic mice expressing wild or mutant tau, and in wild-type (WT) mice. However, little is known about tau propagation following inoculation in the white matter. Objectives: The present study is geared to learning […]

Published on May 28, 2019