Abnormal lipid metabolism in fat cells predicts future weight gain and diabetes in women

Published on May 31, 2018

The inefficient breakdown of fats predicts later weight gain and metabolic complications such as type 2 diabetes in women, researchers report. Low levels of hormone-stimulated lipolysis — a biochemical process by which triglycerides are broken down into energy-rich fatty acids — were associated with weight gain and metabolic problems 13 years later. The researchers also developed an algorithm to detect impairments in hormone-stimulated lipolysis using clinical and blood measures.

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