Imagine alpha-synuclein strains as travelers embarking on a journey from the brain to the body, or vice versa. Along their path, they encounter different cellular environments that can shape their structure and function. This exciting hypothesis suggests that these changing environments may contribute to the development of distinct aggregate strains within different cells, ultimately leading […]
Imagine a peaceful city protected by diligent guards who survey their surroundings with sharp eyes. But suddenly, invading armies of toxic proteins storm in, transforming these guards into voracious warriors with an insatiable appetite for destruction. This scenario mirrors the role of microglia in the development of Alzheimer’s disease (AD). AD is a progressive neurodegenerative […]
Imagine your brain as a symphony, with different instruments playing different roles. In the realm of memory, theta rhythm is like the conductor, orchestrating the flow of information. But what happens when this conductor gets disrupted? That’s where the ApoE gene comes into play. The ApoE epsilon 4 allele, known for its association with cognitive […]
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